uPA (PLAU) Mouse Monoclonal Antibody [Clone ID: OTI1D4]

CAT#: TA805314S

PLAU mouse monoclonal antibody, clone OTI1D4 (formerly 1D4)

Size: 30 ul 100 ul



  View other "OTI1D4" antibodies (4)

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【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 800.00


货期*
现货

规格
    • 30 ul

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经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human plasminogen activator, urokinase (PLAU), transcript variant 1, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of plasminogen activator, urokinase (PLAU), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI1D4
Applications WB
Recommend Dilution WB 1:200
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 107-379 of human PLAU (NP_002649) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 46.3 kDa
Gene Name plasminogen activator, urokinase
Background This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Synonyms ATF; BDPLT5; QPD; u-PA; UPA; URK
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protease
Protein Pathways Complement and coagulation cascades
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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