TLK2 Mouse Monoclonal Antibody [Clone ID: OTI2D10]

Specifications

Product Data
Clone Name	OTI2D10
Applications	IHC
Recommend Dilution	IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-296 of human TLK2(NP_006843) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	85.3 kDa
Gene Name	tousled like kinase 2
Database Link	NP_006843 Entrez Gene 24086 MouseEntrez Gene 303592 RatEntrez Gene 11011 Human UniProt ID Q86UE8
Background	This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Synonyms	HsHPK; PKU-ALPHA
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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