Factor I (CFI) Mouse Monoclonal Antibody [Clone ID: OTI7C8]

CAT#: TA805928S

CFI mouse monoclonal antibody,clone OTI7C8

Size: 30 ul 100 ul



  View other "OTI7C8" antibodies (4)

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【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 800.00


货期*
现货

规格
    • 30 ul

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经常一起买 (3)
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Recombinant protein of human complement factor I (CFI), 20 µg
    • 20 ug

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Transient overexpression lysate of complement factor I (CFI)
    • 100 ug

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Specifications

Product Data
Clone Name OTI7C8
Applications IHC
Recommend Dilution IHC 1:2000
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 340-583 of human CFI(NP_000195) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 63.4 kDa
Gene Name complement factor I
Background This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008]
Synonyms AHUS3; ARMD13; C3b-INA; C3BINA; FI; IF; KAF
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Complement and coagulation cascades
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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