RHOC Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3A5]

Specifications

Product Data
Clone Name	OTI3A5
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide corresponding to C terminal of human RHOC.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21.8 kDa
Gene Name	ras homolog family member C
Database Link	NP_786886 Entrez Gene 11853 MouseEntrez Gene 295342 RatEntrez Gene 389 Human UniProt ID P08134
Background	This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Synonyms	ARH9; ARHC; H9; RHOH9
Reference Data
Protein Families	Druggable Genome

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