BAMBI Mouse Monoclonal Antibody [Clone ID: OTI5D5]

Specifications

Product Data
Clone Name	OTI5D5
Applications	WB
Recommend Dilution	WB 1:200
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 21-152 of human BAMBI(NP_036474) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26.6 kDa
Gene Name	BMP and activin membrane-bound inhibitor
Database Link	NP_036474 Entrez Gene 68010 MouseEntrez Gene 83837 RatEntrez Gene 25805 Human UniProt ID Q13145
Background	This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]
Synonyms	NMA
Reference Data
Protein Families	Transmembrane

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