beta Catenin (CTNNB1) Mouse Monoclonal Antibody [Clone ID: OTI2F10]
CAT#: TA807908S
CTNNB1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10)
Size: 100 ul
View other "OTI2F10" antibodies (4)
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CNY 800.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI2F10 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 29-118 of human CTNNB1(NP_001091679) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | catenin beta 1 |
Database Link | |
Background | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009] |
Synonyms | armadillo; CTNNB; MRD19 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Focal adhesion, Leukocyte transendothelial migration, Melanogenesis, Pathogenic Escherichia coli infection, Pathways in cancer, Prostate cancer, Thyroid cancer, Tight junction, Wnt signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF807908 | Carrier-free (BSA/glycerol-free) CTNNB1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10) |
CNY 3,999.00 |
|
TA807908 | CTNNB1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10) |
CNY 1,999.00 |
|
TA807908AM | CTNNB1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10), Biotinylated |
CNY 3,990.00 |
|
TA807908BM | CTNNB1 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10), HRP conjugated |
CNY 3,990.00 |
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