p21 (CDKN1A) Mouse Monoclonal Antibody [Clone ID: OTI7C8]
CAT#: TA808164
CDKN1A mouse monoclonal antibody, clone OTI7C8 (formerly 7C8)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI7C8" antibodies (4)
Need it in bulk or conjugated?
Get a free quote
CNY 1,999.00
CNY 2,700.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | OTI7C8 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 2-164 of human CDKN1A(NP_510867) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 17.9 kDa |
Gene Name | cyclin-dependent kinase inhibitor 1A |
Database Link | |
Background | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010] |
Synonyms | CAP20; CDKN1; CIP1; MDA-6; P21; p21CIP1; SDI1; WAF1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Bladder cancer, Cell cycle, Chronic myeloid leukemia, ErbB signaling pathway, Glioma, Melanoma, p53 signaling pathway, Pathways in cancer, Prostate cancer |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF808164 | Carrier-free (BSA/glycerol-free) CDKN1A mouse monoclonal antibody, clone OTI7C8 (formerly 7C8) |
CNY 3,999.00 |
|
TA808164AM | CDKN1A mouse monoclonal antibody, clone OTI7C8 (formerly 7C8), Biotinylated |
CNY 3,990.00 |
|
TA808164BM | CDKN1A mouse monoclonal antibody, clone OTI7C8 (formerly 7C8), HRP conjugated |
CNY 3,990.00 |
|
TA808164S | CDKN1A mouse monoclonal antibody, clone OTI7C8 (formerly 7C8) |
CNY 800.00 |