TRBP (TARBP2) Mouse Monoclonal Antibody [Clone ID: OTI7C1]

Specifications

Product Data
Clone Name	OTI7C1
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TARBP2 (NP_004169) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36.7 kDa
Gene Name	TARBP2, RISC loading complex RNA binding subunit
Database Link	NP_004169 Entrez Gene 21357 MouseEntrez Gene 363006 RatEntrez Gene 6895 Human UniProt ID Q15633
Background	HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
Synonyms	LOQS; TRBP; TRBP1; TRBP2
Reference Data
Protein Families	Stem cell - Pluripotency

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