PMP22 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5D1]

Specifications

Product Data
Clone Name	OTI5D1
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PMP22 (NP_000295) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	17.7 kDa
Gene Name	peripheral myelin protein 22
Database Link	NP_000295 Entrez Gene 24660 RatEntrez Gene 5376 Human UniProt ID Q01453
Background	This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms	CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110
Reference Data
Protein Families	Transmembrane

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