NCF4 Mouse Monoclonal Antibody [Clone ID: OTI12H10]

CAT#: TA809153S

NCF4 mouse monoclonal antibody,clone OTI12H10

Size: 30 ul 100 ul



  View other "OTI12H10" antibodies (4)

Need it in bulk or conjugated?
Get a free quote

【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 800.00


货期*
现货

规格
    • 30 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human neutrophil cytosolic factor 4, 40kDa (NCF4), transcript variant 1, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of neutrophil cytosolic factor 4, 40kDa (NCF4), transcript variant 2
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI12H10
Applications IHC
Recommend Dilution IHC 1:500
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NCF4 (NP_000622) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 38.9 kDa
Gene Name neutrophil cytosolic factor 4
Background The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Synonyms NCF; P40PHOX; SH3PXD4
Reference Data
Protein Pathways Leukocyte transendothelial migration
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Other Versions

Customer Reviews 
Loading...