NCF4 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3E8]
CAT#: TA809222AM
NCF4 mouse monoclonal antibody,clone OTI3E8, Biotinylated
Conjugation: Unconjugated HRP
View other "OTI3E8" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI3E8 |
Applications | WB |
Recommend Dilution | WB 1:500 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human NCF4 (NP_000622) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 38.9 kDa |
Gene Name | neutrophil cytosolic factor 4 |
Database Link | |
Background | The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Synonyms | NCF; P40PHOX; SH3PXD4 |
Reference Data | |
Protein Pathways | Leukocyte transendothelial migration |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF809222 | Carrier-free (BSA/glycerol-free) NCF4 mouse monoclonal antibody,clone OTI3E8 |
CNY 3,999.00 |
|
TA809222 | NCF4 mouse monoclonal antibody,clone OTI3E8 |
CNY 1,999.00 |
|
TA809222BM | NCF4 mouse monoclonal antibody,clone OTI3E8, HRP conjugated |
CNY 3,990.00 |
|
TA809222S | NCF4 mouse monoclonal antibody,clone OTI3E8 |
CNY 800.00 |