ROR gamma (RORC) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1G3]

Specifications

Product Data
Clone Name	OTI1G3
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-266 of human RORC (NP_005051) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	RAR related orphan receptor C
Database Link	NP_005051 Entrez Gene 19885 MouseEntrez Gene 368158 RatEntrez Gene 6097 Human UniProt ID P51449
Background	The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	NR1F3; RORG; RZR-GAMMA; RZRG; TOR
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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