SMC1 (SMC1A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5C8]

CAT#: TA809808AM

SMC1A mouse monoclonal antibody,clone OTI5C8, Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI5C8" antibodies (4)

Need it in bulk or conjugated?
Get a free quote

CNY 3,990.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Transient overexpression lysate of structural maintenance of chromosomes 1A (SMC1A)
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Clone Name OTI5C8
Applications WB
Recommend Dilution WB 1:500
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 889-1016 of human SMC1A (NP_006297) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 143.1 kDa
Gene Name structural maintenance of chromosomes 1A
Background Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Synonyms CDLS2; DEE85; DXS423E; EIEE85; SB1.8; SMC1; SMC1alpha; SMC1L1; SMCB
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Other Versions

Customer Reviews 
Loading...