JIP1 (MAPK8IP1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI13F10]

CAT#: TA809926AM

MAPK8IP1 mouse monoclonal antibody,clone OTI13F10, Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI13F10" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), 20 µg
    • 20 ug

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Transient overexpression lysate of mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1)
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Specifications

Product Data
Clone Name OTI13F10
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MAPK8IP1 (NP_005447) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 77.3 kDa
Gene Name mitogen-activated protein kinase 8 interacting protein 1
Background This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011]
Synonyms IB1; JIP-1; JIP1; PRKM8IP
Reference Data
Protein Families Druggable Genome
Protein Pathways MAPK signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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