Topoisomerase I (TOP1) Mouse Monoclonal Antibody [Clone ID: OTI3B9]

Specifications

Product Data
Clone Name	OTI3B9
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 93-151 of human TOP1(NP_003277 ) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	90.5 kDa
Gene Name	topoisomerase (DNA) I
Database Link	NP_003277 Entrez Gene 21969 MouseEntrez Gene 64550 RatEntrez Gene 7150 Human UniProt ID P11387
Background	This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
Synonyms	TOPI
Reference Data
Protein Families	Druggable Genome

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