STARD4 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4G9]

Specifications

Product Data
Clone Name	OTI4G9
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human STARD4 (NP_631903) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23.3 kDa
Gene Name	StAR related lipid transfer domain containing 4
Database Link	NP_631903 Entrez Gene 170459 MouseEntrez Gene 291699 RatEntrez Gene 134429 Human UniProt ID Q96DR4
Background	Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]). [supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AK054566.1, AK290312.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END##
Synonyms	4632419C16Rik; 9030213J02Rik; AA517649; AW324468; StAR-related lipid transfer (START) domain containing 4; StAR-related lipid transfer protein 4
Reference Data

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