RNF14 Mouse Monoclonal Antibody [Clone ID: OTI3A4]

Specifications

Product Data
Clone Name	OTI3A4
Applications	WB
Recommend Dilution	WB 1:200
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-220 of human RNF14 (NP_899647) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	53.7 kDa
Gene Name	ring finger protein 14
Database Link	NP_899647 Entrez Gene 56736 MouseEntrez Gene 619577 RatEntrez Gene 9604 Human UniProt ID Q9UBS8
Background	The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
Synonyms	ARA54; HFB30; HRIHFB2038; TRIAD2
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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