CRMP2 (DPYSL2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5D7]

Specifications

Product Data
Clone Name	OTI5D7
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 13-490 of human DPYSL2 (NP_001377) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	dihydropyrimidinase like 2
Database Link	NP_001377 Entrez Gene 12934 MouseEntrez Gene 25416 RatEntrez Gene 1808 Human UniProt ID Q16555
Background	This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Synonyms	CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Axon guidance

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