Dermcidin (DCD) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3F5]

Specifications

Product Data
Clone Name	OTI3F5
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 20-110 of human DCD (NP_444513) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	9.2 kDa
Gene Name	dermcidin
Database Link	NP_444513 Entrez Gene 117159 Human UniProt ID P81605
Background	This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Synonyms	AIDD; DCD-1; DSEP; HCAP; PIF
Reference Data
Protein Families	Secreted Protein

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