c Maf (MAF) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2B12]

Specifications

Product Data
Clone Name	OTI2B12
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MAF (NP_001026974) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Gene Name	MAF bZIP transcription factor
Database Link	NP_001026974 Entrez Gene 17132 MouseEntrez Gene 54267 RatEntrez Gene 4094 Human UniProt ID O75444
Background	The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Synonyms	AYGRP; c-MAF; CCA4; CTRCT21
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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