TIGIT Mouse Monoclonal Antibody [Clone ID: OTI3B6]

Specifications

Product Data
Clone Name	OTI3B6
Applications	FC, WB
Recommend Dilution	WB 1:1000, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TIGIT (NP_776160) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26.1 kDa
Gene Name	T-cell immunoreceptor with Ig and ITIM domains
Database Link	NP_776160 Entrez Gene 201633 Human UniProt ID Q495A1
Background	This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. [provided by RefSeq, Sep 2009]
Synonyms	VSIG9; VSTM3; WUCAM
Reference Data
Protein Families	Transmembrane

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