Papillary renal cell carcinoma (PRCC) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5G7]

Specifications

Product Data
Clone Name	OTI5G7
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 135-491 of human PRCC (NP_005964) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.2 kDa
Gene Name	papillary renal cell carcinoma (translocation-associated)
Database Link	NP_005964 Entrez Gene 94315 MouseEntrez Gene 310687 RatEntrez Gene 5546 Human UniProt ID Q92733
Background	This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010]
Synonyms	RCCP1; TPRC
Reference Data
Protein Families	Druggable Genome

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