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Caspase 3 (CASP3) Mouse Monoclonal Antibody [Clone ID: OTI3A12]
CAT＃: TA813275
CASP3 mouse monoclonal antibody,clone OTI3A12
Size: 30 ul
Formulation: Carrier-Free
View other "OTI3A12" antibodies (4)
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CNY 1,999.00
CNY 2,700.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 3,080.00
CNY 9,998.00
CNY 3,080.00
Specifications
| Product Data | |
| Clone Name | OTI3A12 |
| Applications | IHC, WB |
| Recommend Dilution | WB 1:500, IHC 1:500 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29-219 of human CASP3 (NP_116786) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 31.4 kDa |
| Gene Name | caspase 3 |
| Database Link | |
| Background | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008] |
| Synonyms | CPP32; CPP32B; SCA-1 |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protease |
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, Huntington's disease, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Viral myocarditis |
Documents
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| CF813275 | Carrier-free (BSA/glycerol-free) CASP3 mouse monoclonal antibody,clone OTI3A12 |
CNY 3,999.00 |
|
| TA813275AM | CASP3 mouse monoclonal antibody,clone OTI3A12, Biotinylated |
CNY 3,990.00 |
|
| TA813275BM | CASP3 mouse monoclonal antibody,clone OTI3A12, HRP conjugated |
CNY 3,990.00 |
|
| TA813275S | CASP3 mouse monoclonal antibody,clone OTI3A12 |
CNY 800.00 |
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