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CD45 (PTPRC) Mouse Monoclonal Antibody [Clone ID: OTI1E1]
CAT＃: TA813922
CD45 mouse monoclonal antibody, clone OTI1E1
Size: 30 ul
Formulation: Carrier Free
View other "OTI1E1" antibodies (4)
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CNY 1,999.00
CNY 3,600.00
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CNY 4,840.00
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Clone Name | OTI1E1 |
| Applications | IHC |
| Recommend Dilution | IHC 1:16000 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 931-1165 of human CD45 (NP_002829) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Predicted Protein Size | 147.1 kDa |
| Gene Name | protein tyrosine phosphatase, receptor type C |
| Database Link | |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] |
| Synonyms | B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway |
Documents
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| CF813922 | Carrier-free (BSA/glycerol-free) CD45 mouse monoclonal antibody, clone OTI1E1 |
CNY 3,999.00 |
|
| TA813922AM | CD45 mouse monoclonal antibody, clone OTI1E1, Biotinylated |
CNY 3,990.00 |
|
| TA813922BM | CD45 mouse monoclonal antibody, clone OTI1E1, HRP conjugated |
CNY 3,990.00 |
|
| TA813922S | CD45 mouse monoclonal antibody, clone OTI1E1 |
CNY 800.00 |
