Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: OTI1E7]
CAT#: TA814221S
NEFL mouse monoclonal antibody, clone OTI1E7
Size: 100 ul
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CNY 800.00
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CNY 300.00
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CNY 2,900.00
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Specifications
Product Data | |
Clone Name | OTI1E7 |
Applications | ELISA |
Recommend Dilution | ELISA 1:5000-10000 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 401-543aa of human NEFL (NP_006149) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 61.5 kDa |
Gene Name | neurofilament, light polypeptide |
Database Link | |
Background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] |
Synonyms | CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
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