NF-kB p65 (RELA) Rabbit Polyclonal Antibody
CAT#: TA890002
Rabbit polyclonal RELA Antibody
Size: 30 ul
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CNY 1,999.00
CNY 2,700.00
Cited in 3 publications. |
CNY 4,840.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 9,998.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide conjugated to KLH derived from within residues 100 - 170 of Human RELA. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from the immunized serum by affinity chromatography (Protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 60 kDa |
Gene Name | RELA proto-oncogene, NF-kB subunit |
Database Link | |
Background | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Synonyms | NFKB3; p65 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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Influence of hyperocclusion on the remodeling of gingival tissues
,Li, Y;Wang, Z;Liu, Y;Zhang, H;Huang, Y;Gao, P;Hu, Y;Xu, Q;,
International immunopharmacology
,PubMed ID 34153669
[RELA]
|
Upstream transcription factor 1 prompts malignancies of cervical cancer primarily by transcriptionally activating p65 expression
,null,
Experimental and Therapeutic Medicine
,PubMed ID 30542391
[RELA]
|
The Effects of Interleukin-17 (IL-17)-Related Inflammatory Cytokines and A20 Regulatory Proteins on Astrocytes in Spinal Cord Cultured In Vitro
,Zong, S;Li, K;Zeng, G;Fang, Y;Zhao, J;,
Cell. Physiol. Biochem.
,PubMed ID 26938714
[RELA]
|
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