C1QA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human recombinant protein fragment of human C1QA ( NP_057075) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	complement component 1, q subcomponent, A chain
Database Link	NP_057075 Entrez Gene 712 Human UniProt ID P02745
Background	This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Reference Data
Protein Families	Secreted Protein
Protein Pathways	Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

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