XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: UMAB21]

Specifications

Product Data
Clone Name	UMAB21
Applications	10k-ChIP, IF, IHC, WB
Recommend Dilution	WB 1:200~500, IF 1:100, FLOW 1:100, IHC 1:500
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human XPF (NP_005227) produced in HEK293 cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	104.3 kDa
Gene Name	ERCC excision repair 4, endonuclease catalytic subunit
Database Link	NP_005227 Entrez Gene 50505 MouseEntrez Gene 304719 RatEntrez Gene 479842 DogEntrez Gene 712641 MonkeyEntrez Gene 2072 Human UniProt ID Q92889
Background	The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
Synonyms	ERCC11; FANCQ; RAD1; XFEPS; XPF
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Nucleotide excision repair

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