IRF6 Mouse Monoclonal Antibody [Clone ID: UMAB106]

Specifications

Product Data
Clone Name	UMAB106
Applications	IF, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:100
Reactivity	Human, Monkey, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human IRF6(NP_006138) produced in HEK293 Cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.9 kDa
Gene Name	interferon regulatory factor 6
Database Link	NP_006138 Entrez Gene 54139 MouseEntrez Gene 364081 RatEntrez Gene 480015 DogEntrez Gene 3664 Human UniProt ID O14896
Background	This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Synonyms	LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transcription Factors

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