p63 (TP63) Mouse Monoclonal Antibody [Clone ID: UMAB4]
CAT#: UM570004
TP63 mouse monoclonal antibody, clone UMAB5
Size: 100 ul
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CNY 1,150.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | UMAB4 |
Applications | IHC, WB |
Recommend Dilution | WB 1:500, IHC 1:200 |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human TP63 (NP_003713) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 76.8 kDa |
Gene Name | tumor protein p63 |
Database Link | |
Background | This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. |
Synonyms | AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM500004 | TP63 mouse monoclonal antibody, clone UMAB4 |
CNY 2,999.00 |
|
UM500004CF | TP63 mouse monoclonal antibody, clone UMAB4 |
CNY 4,999.00 |