OLIG2 Mouse Monoclonal Antibody [Clone ID: UMAB294]

Specifications

Product Data
Clone Name	UMAB294
Applications	IHC
Recommend Dilution	IHC 1:200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment of human OLIG2 (NP_005797) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1.00mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Predicted Protein Size	32.2 kDa
Gene Name	oligodendrocyte transcription factor 2
Database Link	NP_005797 Entrez Gene 10215 Human UniProt ID Q13516
Background	This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
Synonyms	BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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