p53 (TP53) Mouse Monoclonal Antibody [Clone ID: UMAB206]
CAT#: UM870098
P53 (TP53) mouse monoclonal antibody, clone UMAB206
Size: 100 ul
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CNY 1,150.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | UMAB206 |
Applications | 10k-ChIP, IF, IHC, WB |
Recommend Dilution | IHC 1:100~200 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human TP53 (NP_000537) produced in SF9 cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 44.1 kDa |
Gene Name | tumor protein p53 |
Database Link | |
Background | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013] |
Synonyms | BCC7; LFS1; P53; TRP53 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM800098 | P53 (TP53) mouse monoclonal antibody, clone UMAB206 |
CNY 2,999.00 |
|
UM800098CF | Carrier-free (BSA/glycerol-free) P53 (TP53) mouse monoclonal antibody, clone UMAB206 |
CNY 4,999.00 |