Human PCSK9 ELISA Kit

CAT#: EA100676

Human PCSK9 ELISA Kit



CNY 5,000.00


货期*
3周

规格
    • 1 x 96 wells

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Specifications

Product Data
Description Human PCSK9 ELISA Kit
Size 1 x 96 wells
Assay Type Sandwich ELISA kit of Quantitative Detection for Human PCSK9
Assay Length 3.5 hours incubations; 1 hour washing and analyzing samples
Signal Colorimetric
Curve Range 156pg/ml-10,000pg/ml
Sample Type Cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Sample Volume 100 ul
Specificity This kit is used for quantitative detection of human PCSK9
Sensitivity <10pg/ml
Reactivity Human
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • 96-well plate precoated with anti- human PCSK9 antibody | 1
  • Lyophilized recombinant human PCSK9 standard 10ng/tube | 2
  • Biotinylated anti- human PCSK9 antibody 130ul (dilution 1:100) | 1
  • Avidin-Biotin-Peroxidase Complex(ABC) 130ul (dilution 1:100) | 1
  • Sample diluent buffer 30ml | 1
  • Antibody diluent buffer 12ml | 1
  • ABC diluent buffer 12ml | 1
  • TMB color developing agent 10ml | 1
  • TMB stop solution 10ml | 1
  • Wash Buffer (25 x) 20ml | 1
  • Plate Sealers | 4
Background Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.
Gene Symbol PCSK9
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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