Human CD130 (GP130) ELISA Kit, 1 x 48-well (pre-coated)

Specifications

Product Data
Description	Human CD130 (GP130) ELISA Kit, 1 x 48-well (pre-coated)
Size	1 x 48 wells (pre-coated)
Format	1 x 48-well (pre-coated)
Assay Type	Solid Phase Sandwich ELISA
Assay Length	1h40min
Signal	Colorimetric
Curve Range	56.25-1800 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sample Volume	100 µl
Specificity	Recognizes both natural and recombinant human soluble gp130
Sensitivity	15 pg/ml
Cross Reactivity	No cross reactivity with other human soluble receptors. No interference with neither soluble gp80 nor IL-6.
Interference	No significant interference observed with available related molecules.
Components	ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background	The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Gene Symbol	IL6ST
Standard Curve	Representative Standard Curve

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