Human CD124 ELISA Kit, 1 x 96-well (pre-coated)
CNY 5,401.00
货期*
6周
规格
Specifications
Product Data | |
Description | Human CD124 ELISA Kit, 1 x 96-well (pre-coated) |
Size | 1 x 96 wells (pre-coated) |
Format | 1 x 96-well (pre-coated) |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 1h45min |
Signal | Colorimetric |
Curve Range | 31.25-1000 pg/ml |
Sample Type | Serum, Plasma, Cell culture supernatant |
Sample Volume | 100 µl |
Specificity | Recognizes both natural and recombinant human soluble IL-4R |
Sensitivity | 11.5 pg/ml |
Cross Reactivity | No cross reactivity with other human soluble receptors |
Interference | No significant interference observed with available related molecules. |
Components | ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure. |
Background | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012] |
Gene Symbol | IL4R |
Standard Curve |
![]() Representative Standard Curve
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