Human CD95 ELISA Kit, 1 x 48-well (pre-coated)

CAT#: EA101205

Human CD95 ELISA Kit, 1 x 48-well (pre-coated)



CNY 3,060.00


货期*
6周

规格
    • 1 x 48 wells (pre-coated)

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Specifications

Product Data
Description Human CD95 ELISA Kit, 1 x 48-well (pre-coated)
Size 1 x 48 wells (pre-coated)
Format 1 x 48-well (pre-coated)
Assay Type Solid Phase Sandwich ELISA
Assay Length 1h45min
Signal Colorimetric
Curve Range 93.75-3000 pg/ml
Sample Type Serum, Plasma, Cell culture supernatant
Sample Volume 100 µl
Specificity Recognizes both natural and recombinant soluble human Fas
Sensitivity 47 pg/ml
Cross Reactivity No cross reactivity with other human soluble molecules
Interference No significant interference observed with available related molecules.
Components ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]
Gene Symbol FAS
Standard Curve
Representative Standard Curve
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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