Human Perforin ELISA Set, 5 x 96-well

Specifications

Product Data
Description	Human Perforin ELISA Set, 5 x 96-well
Size	5 x 96 wells
Format	5 x 96-well
Assay Type	Solid Phase Sandwich ELISA
Assay Length	From sample to end 3h45min
Signal	Colorimetric
Curve Range	62.5-2000 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sample Volume	100 µl
Specificity	Recognizes both natural and recombinant human Perforin
Sensitivity	40 pg/ml
Cross Reactivity	No cross reactivity with other human soluble molecules
Components	ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
Background	The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Symbol	PRF1

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