Human IL-1 beta ELISpot Set, 15 x 96-well (plates not included)
CNY 14,813.00
货期*
6周
规格
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Specifications
Product Data | |
Description | Human IL-1 beta ELISpot Set, 15 x 96-well (plates not included) |
Size | 15 x 96 wells (plates not included) |
Format | 15 x 96-well (plates not included) |
Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
Assay Length | 3h after cell stimulation |
Signal | Colorimetric |
Specificity | Recognizes natural (pro and mature) human IL-1b |
Cross Reactivity | No cross reactivity with other human cytokines |
Components | ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, and blocking reagent. |
Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
Gene Symbol | IL1B |
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