Human DR6 (TNFRSF21) ELISA KIT (1 x 96 wells)
CAT#: EA102681
For quantitative detection of human TNFRSF21 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
CNY 5,000.00
货期*
3周
规格
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Specifications
Product Data | |
Description | For quantitative detection of human TNFRSF21 in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
Size | 1 x 96 wells |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human TNFRSF21/DR6 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 15.6pg/ml-1000pg/ml |
Specificity | This kit is used for quantitative detection of Human TNFRSF21/DR6 |
Sensitivity | <10pg/ml |
Reactivity | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Death receptor 6 (DR6), also known as tumor necrosis factor receptor superfamily member 21 (TNFRSF21), is a cell surface receptor of the tumor necrosis factor receptor superfamily which activates the JNK and NF-κB pathways. This gene is mapped to 6p12.3. This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. |
Gene Symbol | TNFRSF21 |
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