Equine BMP2 ELISA KIT (1 x 96 wells)

Specifications

Product Data
Description	Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine BMP-2. 96wells/kit, with removable strips.
Size	1 x 96 wells
Format	8x12 divisible strips
Assay Type	Sandwich ELISA kit of Quantitative Detection for Equine BMP2
Assay Length	3.5 hours incubations; 1 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	31.2pg/ml-2000pg/ml
Specificity	This kit is used for quantitative detection of Equine BMP2
Sensitivity	<2pg/ml
Reactivity	Equine
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Components	10ng/tube
Background	Bone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant horse equine BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.
Gene Symbol	BMP2

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