Human Angiotensin Converting Enzyme 2 (ACE2) ELISA KIT (1 x 96 wells)

Specifications

Product Data
Description	Human Angiotensin Converting Enzyme 2 (ACE2) ELISA KIT (1 x 96 wells)
Size	1 x 96 wells
Format	8x12 divisible strips
Assay Type	Sandwich
Assay Length	4 hours incubations; 1 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	78pg/ml-5000pg/ml
Sample Type	Cell culture supernates, serum and plasma (heparin).
Sample Volume	100µl
Specificity	This kit is used for quantitative detection of Human ACE2
Sensitivity	19.88pg/ml
Reactivity	Human
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Interference	No significant interference observed with available related molecules.
Components	ACE2 Antibody Coated 96-well Plate in foil pouch with desiccant|1 plate Recombinant Human ACE2 Standard (250ng/ml)| 0.1 mL 100x Biotinylated HumanACE2 Detection Antibody| 0.12 mL Assay Buffer| 30 mL Sample Diluent|12 mL 100x Peroxidase Conjugate| 0.12 mL Wash Buffer Concentrate 20X| 60 mL Substrate|12 mL Stop Solution|12 mL
Background	Angiotensin I-converting enzyme 2 (ACE2) is a protein belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. By sequence similarity to a sequence in GenBank, this gene is mapped to Xp22.2. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2.
Gene Symbol	ACE2
Standard Curve	Data image for Human ACE2 ELISA kit.

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