Human LTA ELISA KIT (96 T)

Specifications

Product Data
Description	Human TNF-β Immunoassay
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	31.25-2000pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant human TNF-β.
Sensitivity	15pg/mL
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,2000 pg/ml upon reconstitution,2 vials Concentrated Biotin-Conjugated antibody(100X) - 120 ul/vial,1 vials Concentrated Streptavidin-HRP solution(100X) - 120 ul/vial,1 vial Standard /Sample Diluent - 16 ml/vial,1 bottle Biotin-Conjugate antibody Diluent - 16 ml/vial,1 bottle Streptavidin-HRP Diluent - 16 ml/vial,1 bottle Wash Buffer Concentrate (20x) - 30 ml/vial,1 bottle Substrate Solution - 12 ml/vial,1 bottle Stop Solution - 12 ml/vial,1 bottle Plate Cover Seals,4 pieces
Background	Tumor Necrosis Factor-β (TNF-β), also known as Lymphotoxin-α (LT-α), is a member of the TNF Superfamily. Human LT-α/TNF-β is a 22 kDa protein that shares 73% amino acid sequence identity with mouse and rat LT-α/TNF-β. Secreted LT-α forms homotrimers that bind and activate TNF RI/TNFRSF1A, TNF RII/TNFRSF1B, and HVEM/TNFRSF14. LT-α/TNF-β also forms heterotrimers with plasma membrane-localized LT-β to bind and activate the LT-β R/TNFRSF3. In addition to its cytotoxic action on tumor cells, LT-α/TNF-β mediates lymph node development, inflammation, and immune function. LT-α/TNF-β is expressed in activated T and B lymphocytes and contributes to autoimmune disease.
Gene Symbol	LTA

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