RPS19 (NM_001022) Human 3' UTR Clone

Specifications

Product Data
Product Name	RPS19 (NM_001022) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DBA; DBA1; eS19; LOH19CR1; S19
ACCN	NM_001022
Insert Size	1578 bp
Sequence Data	Insert Sequence (showhide) >SC200141 3’UTR clone of NM_001022 The sequence shown below is from the reference sequence of NM_001022. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGTGGCAGCTGCCAACAAGAAGCATTAGAACAAACCATGCTGGGTTAATAAATTGCCTCATTCGTAA TCCTGGTCTGGGTCTCTTTTTTGAGTCTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCCATCTC AGCTCACTGCAATCTCCGCCTTCTGGGTTCAAATGATTCTCCTGCCTCAGCCTCCCAAAGTGCTGGGAT TACAAGTGTGAGCCACTGTGCCTGGTCTGGTTTGGGTCTCTTGATTGTTCTTCAGGGGCATGAGGAAGA GGCGCTTCCTCCCTTCCCTTGGGTGAGGGGGCCCAGGGTGATTGGGTGGCTGTTTACCCGGCAGCCAGT CGGGCCTTCCCAGGTCAAACAGTTCCCATCTGGGTTTGGAGGAAGGACCCAGGGGCCCTTGTGGCTCAC TCCCCCACATCCTGTCTTTGCAATTGTCAGAAAGTGAGAAACGAAAGGATGGCTGTGAGCTGTGACCTC AGCTGGGCCTGGGCTGCAGAGGTGGCTTCCGCTGGAGTAAAGCAAGAGGGCCCAGGGTTCATGCTCTTC CCTGGAAGGTAGAAAAGGACAGACCACCAGGGAGCCTCCACCGCAAACTGACCTGTGCTGCCTACACAC TAACTTTCCTGGGCCTGGGGCCTGCACAGGCTGAATGGTCCTTGAGCCTTCACTCTGCATCTGAGCGGT CTTGGGCCCGCTGAGTGGCAGTGGCAGGAAGTCGGTGGAAGCAGATCCCTGTGCAGAAGTTGAATTACC AGGGCGGCCACACACGGGCTGCACAACCTTTGCAGTCGTGCACGGCAAGTGGGATGTGGCCTCCGCCCA TGATTGGGCACCTGGTCAGGCTGGGAGATCCAAATAGCACCCAGTGGGCAGCTGTCCGACCCCTGGAGG GGCAAGCCAGGAAAGAAACTTAGGGCCCGCTGTGACCAGATGTCCCTCCCAGTTGGGAAGACTAAACTG GTTTGGCCAATATCTCCCAGGATTCCCCTGTCCAAATTATTCCTGGGATCTGACCCATTTCCTGGAAAG GGGCGAGCCTGGGTTTTGAAGTTCAAACTAGAGTTTAAATCACAACTCTGCCCCTAATCCCACGTAACC CTGTGCACCTTATCCTCTGAGCCTTCGTCTCCTCGTGTGTAAGCCTGCTAACTCCTGAGAGACTGGACA AGATGCCGTGGAGAGCCTTGGCTCTGAGTAGCTCTGCTGCTGGACAGTTCAGTTGGCAGTCCCCAAACG TAAGGCGTAAGAGTTTAAGAAGTATCGGCCAGGCACAGTGGCTCACACCTGTAATCTCAACACTTTGGG AGGCCGAGACGGGCTGATCACCTGAGGTTGGGAGCTTGAGAACAGCCTGACCAACATGGAGAAACCCTG TCTCTAAAAATACCAAAATTAGTTGGGCATGGTGGCGCGCACCTGTAATCCCAGCTACTCAGGAGGCTG AGGCAGAAGAATCGCTCGAACCCCGGAGGCGGAGGTTGCAGTGGGTTGAGATCGAGCAATTGCAATCCA GCCTGGGCAACAGAGCGAGACTCCATTTCAAAAAAAGAATCAATAAAAATGTTAAAAGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001022.4
Synonyms	DBA; DBA1; eS19; LOH19CR1; S19
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Locus ID	6223
MW	57.5

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