ITGA8 (NM_003638) Human 3' UTR Clone

Specifications

Product Data
Product Name	ITGA8 (NM_003638) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_003638
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC200216 3’UTR clone of NM_003638 The sequence shown below is from the reference sequence of NM_003638. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGACAAATGACAAGACCCCTGAGGCATGACAAGAAAAAAAAAGAAGACCAAAGACCTCAAACACTGGT CCTGTTCAAAGAAAAAGAAAGAACATGAGGGTTAAAAATCAAAGCTTTCTGATACCTGACAGTGACCCA GGAAATGGAGGGGACCCTGGAAACATCACCTCATCTACACCGCACTTTGGAGAAATTGTCCTGGGTGCC CAGTGAGCCCTGTTGGAAAAGGAAACACCAAAGCTGGAGAAGCCATCAGCAATTGTGGAAGATTTTCTT TTGCTTTAATCGTTCTGTACTTGGCAGACACTTTGAAATGCGTATGGGAACGTAAGTTGCAGTCCAGAT CAATCCAGCATAAGTTGCAGAGATGAAATGTCTGAATCACTATAGAATTTACAAGGTGAACTAAGGTGA AATGACTGATTTACTATAGAACTTAGAACTAAGACCACACCATCCAACACTACTGTATCCAATGGAACA TTTGACACCTCCCTATGGAAAAGAAACATTTCTAAGGACATTATGGCTCAGGGAGACAAGCAATATGTT GTTGGTACTGTGAAAGTACTTTTGAAAGGACAAAAATAATCTTGTGAGTGAGGGTGAGAGTTTATTTAT TTATTTTCCATGTCTCTAGGTTGAGAATCTGTCATCTAGAGAATTTGGAAATTAAGATTTGGTTAGCTA GTTTTCAAAATCACTCACTCAGTTTCCTCCTAAGAACCACTGTGTGCAGATAACTCATTTAGCAGAGCT TCTTCAGAATTTAGACAGTGCTAAGGAAAGGAAGATTGGCATTAGGAATCAGTTCTATTTAATACCTTG CTGCCTTCCATCTGAAATTCCTTTCACTCACATTATCCAGGGACTCACATCTGCTTAATTTAGCTTTGC AAGATGTTGCATTTATATTTCCTTGTATATCTTTCCATTGACTTAGTTAATACATGAATTTCGAGGTAC TCTCTACCTTTGGAGTGTTTAAAAGTCATGGTAAAATGTCTAGAGTTCATTAATTAAAAAGCAATTTAA CATTATGGGTAAACATTATTTTTAATATCTATAAGAAGCAACACTTCTTATAGATATTTAGCTTGGGAT TAAATACCCGTTTTTCCTGCTATGCCTTGTACTTGTATACACAGAGAAAACATGTTGAATATAACTTAG ACAAAAACATAAAATTATACAGGCATGAGCCAAACTGGGAAAACTGATTCCTAAAGATTTTTATTTAAA ATTGCTTATTCCAACTTTATTACTTATTTTTACTGCTAATCTTTATAATATGTAACTTTGGAGAATAAT CTTTTATTTAAGCTATTTTCCCATCATCTTGAATTTAACCATCACAAATTTTTTATGTTTAAAACTCTT GTAAATAATTCATAATCTTGTAATATTATCATTTTTGAAGTAAAATTGACCAGCCAAATTTATAGGTAG TCTGCACAATTTTGTATCCTTTTTTAATAATGAAAAATTACTATGAAGAAATACTGAACAAATTTTTAT GTGCAATATTTTATAGACCTATGTATCTGAAGCATGTTTACACTGGCGTTTTTTTTTTTAATTAATTTC CTAAATGTTAAGTATGATAGAACAAGCTGACCCAAATCCTTAAGTTTACAAAGCTGTTGGAAAACTTTG TGTCCTGATTTCAACAATCACGCTTTGTTTGAAAGATGAGCCAAGCTCACAGACACTAAATTTTATGTC ATGCCATAAGCTGGAGAGGAGCCATTTGGCTACAGCTGCGGAACTTCATTGAGGAGCAAATGAAAGGCA CATGGACGAGCACGCTGGTGCAGTTCATGTTCTTCCTGCCTGTGAATTGAATACTGTCCTGGTAGCAGT TTCGGGTCGGTCAGGAGCTCAAGGCTGGTTTGTGTGGCTGACTACGGATGAGCACTGAAGTTGCCTCAA AGAATTAAGGGGTGTCCACACCAGCCTCTGGGGGTCTTTGGTGTTAGTCTTCCAGGTAGAGCTGGTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003638.3
Summary	Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014]
Locus ID	8516
MW	76

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