hemoglobin subunit gamma 1 (HBG1) (NM_000559) Human 3' UTR Clone

Specifications

Product Data
Product Name	hemoglobin subunit gamma 1 (HBG1) (NM_000559) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HBG-T2; HBGA; HBGR; HSGGL1; PRO2979
ACCN	NM_000559
Insert Size	120 bp
Sequence Data	Insert Sequence (showhide) >SC200439 3’UTR clone of NM_000559 The sequence shown below is from the reference sequence of NM_000559. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCCAGTGCCCTGTCCTCCAGATACCACTGAGCTCACTGCCCATGATTCAGAGCTTTCAAGGATAGGCTT TATTCTGCAAGCAATACAAATAATAAATCTATTCTGCTGAGAGATCACACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000559.3
Synonyms	HBG-T2; HBGA; HBGR; HSGGL1; PRO2979
Summary	The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
Locus ID	3047
MW	4.6

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