XPG (ERCC5) (NM_000123) Human 3' UTR Clone

Specifications

Product Data
Product Name	XPG (ERCC5) (NM_000123) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC
ACCN	NM_000123
Insert Size	122 bp
Sequence Data	Insert Sequence (showhide) >SC200561 3’UTR clone of NM_000123 The sequence shown below is from the reference sequence of NM_000123. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGTGCGAGGGGAAGAAAAAGGAAAACCTAATTAAAAAATATGTATCCTCTATAATTAGTTATGACAGCC ATTTGTAATGAATTTGTCGCAAAGACGTAATAAAATTAACTGGTGGCACGGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000123.4
Synonyms	COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC
Summary	This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
Locus ID	2073
MW	4.7

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