PKN1 (NM_213560) Human 3' UTR Clone
CAT#: SC200625
3' UTR clone of protein kinase N1 (PKN1) transcript variant 1 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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Specifications
Product Data | |
Product Name | PKN1 (NM_213560) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | DBK; PAK-1; PAK1; PKN; PKN-ALPHA; PRK1; PRKCL1 |
ACCN | NM_213560 |
Insert Size | 105 bp |
Sequence Data |
>SC200625 3’UTR clone of NM_213560
The sequence shown below is from the reference sequence of NM_213560. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACTTCGACTTCGTGGCCGGGGGCTGCTAGCCCCCTCCCCTGCCCCTGCCCCTGCCCCTGCCCGAGAGC TCTTAGTTTTTAAAAAGGCCTTTGGGATTTGCCGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_213560.3 |
Synonyms | DBK; PAK-1; PAK1; PKN; PKN-ALPHA; PRK1; PRKCL1 |
Summary | The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Locus ID | 5585 |
MW | 3.7 |
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