RPC62 (POLR3C) (NM_006468) Human 3' UTR Clone

Specifications

Product Data
Product Name	RPC62 (POLR3C) (NM_006468) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C82; RPC3; RPC62
ACCN	NM_006468
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC200957 3’UTR clone of NM_006468 The sequence shown below is from the reference sequence of NM_006468. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACATTGAGTGCACCATGAAGAGACAGTGATCCAGAAGAAGCATCTTCCTCAGAAGATCTGGGGGGATG GAAAGCAAAATAAAGGAGGTGCCTGGATGCATTATTTGCAGTGGGATAAGTCGCAGAGTCTTCAACTAA ACCCCCCTCTCTATCCCCTGCAGCCCAGGATACACCTGAAAGAATTTGGCATATTTAGATCCATTGCTG TAGTCTCCCCTCATCAAATCTTGGCAGTGGGAAGAACCTTAAATCAACAAGGTTAATCATCTATCAGAT GCATCTGTTCCCATAAAGAAGTTACCCACACCTATGGTTACCTATATCCCTGGCAATAGGAAACTTCCT AAGAAGTTAATTTTATTTTCAGATGTCTATGCCTGTTCTTTATTTTGTTGAGATAGGTGATAGATAGAT AGATAGATAGATAATTTGTTGTTGTTGAGACAGGATCTCACTCTGTCACTCAGGCTGGGGTGTAATAGC GCAATCACAGCTCCCTACAGCCTTGACCTCCTGAGCTCAAGCAGTCCTTCCACCTCAGCCTCTGGAGTA GCTGGGACTACAGGCATGCACCACACATACCCAGCTATTTTTTATTTATTTATTTATTTTTTTGTAGAG ACAGGGCCTCCCTGTGTTGCCCAGGCTGATGAACTGTAATTTTTAACACACACAGTGTAGGGAATGTGA AAGACTATCACAGAGTAGAAGAAAAAATTATTTTCAGGGTTAGCAGGTGGATTGTCCCAAGCAGTCACA CTAGAATCTGTGGACTGAAGCCACATTTGCCAGCTCCAGGCTTCTAACACATCTGAAACTGTGTATGTA GAACAGCTAGCTCAATGCCTGGCATATGGTAAGCACACAGTAAATTAGCGCCTTCCTCTTCTCCATGGT TCCTTAAAACTGGCAACGCTAAATTCTCTCTCTCAGTATCACGGATATAATTTGTCCCAGCAGCTTTAA TTCATTTAAAGCAGTTAGATGTTTTATAATATCTTCAGTTTTCTCTCACCAATGTGTTTTCTAATTGTT TAAACACTTGAGTGTCAAACAATTGCCAGCCACCATACTAAACACAACATACAAGGATAGATAAATAAG ACACCATCTCTGCCCTCAAGCCAGTCACCATCATTTACTAAGCACCTGTTTTGTGCTAAGTACTGGGGT AAGCCTTGGGGATATAAAGATTAATAAATTTTGAGCATACAGTCTAGTAGGAGGAGACAAATAAGTACA TAAGTACCAGGAAGTATTAGGGGTGCTACAGTAGAAGAGTAAACACTATGTACAGAGAGGCCAGAAAGG GAAAAGGGTCAGGCAGGGAAGGGAACACAGAGAGTGACAATGTATAGTTTGAAAGATGAGGATGCTTTA TTTGCAAACTATCTTAACAAGGGATTCGTAACCAGAATATATAAGGAGCTCAAACAATAGCAAAAAGAA CAATCCAACTTAAAAATGGCCAAAAGATCTTAATAGGTAGTTTTCGAAAGAAGATACACAAATGGCCGA CAGATACATCAAAAAATGTTCAACATCACTAATCAGAGAAATGGAAATCAAAATCAATGAGATAACATC TCACCCCAATTCATTACTTTTATCAAGAAGAAAGAATGAATGCTAGTGAGGATGTGGAAAAAGGAGAGC CCTGCCTGGTACACTGTTGGGAATGTAAATTGGTACAGCCACTGTGGAAGACTACAGAGGTTCCTCAAA AAACTAAAAACAGAACTATGCTCCAGCAGTTCCACTACTGGGTATATATATATCTCCAAAAGGAAAGAA ATCAATGTATCAAAAAGATACCTGCACTCCCATGTTTATTGCAGCAGTATTCACGATAGCCAAAACATG GAATCAACCTAAGTGCCCATCAATAGATGAAAGGCTAAAGAAAATGTATTATTCAGCCATAAGAATGAA TGAAATCCTGTCATTGGCAGCAACATGGATGGAATTGGAGGTCATTATGTTAAGTAAAATAAACCAAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006468.8
Synonyms	C82; RPC3; RPC62
Summary	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds single-stranded DNA (ssDNA) in a sequence-independent manner (PubMed:21358628).[UniProtKB/Swiss-Prot Function]
Locus ID	10623
MW	75.6

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.