Troponin T1 (TNNT1) (NM_003283) Human 3' UTR Clone

Specifications

Product Data
Product Name	Troponin T1 (TNNT1) (NM_003283) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ANM; NEM5; STNT; TNT; TNTS
ACCN	NM_003283
Insert Size	247 bp
Sequence Data	Insert Sequence (showhide) >SC201130 3’UTR clone of NM_003283 The sequence shown below is from the reference sequence of NM_003283. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGGCCGCGTTGGAGGCCGCTGGAAGTGAGGATGCCGCCCCGGACAGTGGCACCTGGGAAGCCTGGGA GTGTTTGTCCCATCGGTAGCTTGAAATAAACGCTCCCCTCAGACACCCGCTGGGTTCTCTGATGTTATT ATGGTTGAGATGCAGCTGGTCTCTCCTGGTTAATTGACTTCTTATTACCAACAAGTTACTTGAAAGAGT GTCACCAATAATCATTAAAGTACGGCAGGCTGAACCTTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003283.6
Synonyms	ANM; NEM5; STNT; TNT; TNTS
Summary	This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	7138
MW	8.9

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