TLR9 (NM_017442) Human 3' UTR Clone
CAT#: SC201161
3' UTR clone of toll-like receptor 9 (TLR9) transcript variant A for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 3 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | TLR9 (NM_017442) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | CD289 |
ACCN | NM_017442 |
Insert Size | 167 bp |
Sequence Data |
>SC201161 3’UTR clone of NM_017442
The sequence shown below is from the reference sequence of NM_017442. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACTTCTGCCAGGGACCCACGGCCGAATAGCCGTGAGCCGGAATCCTGCACGGTGCCACCTCCACACTC ACCTCACCTCTGCCTGCCTGGTCTGACCCTCCCCTGCTCGCCTCCCTCACCCCACACCTGACACAGAGC AGGCACTCAATAAATGCTACCGAAGGCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_017442.4 |
Synonyms | CD289 |
Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017] |
Locus ID | 54106 |
MW | 5.7 |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
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Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis
,null,
Frontiers in Immunology
,PubMed ID 30072988
[TLR9]
|
Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
,null,
Molecular pharmacology
,PubMed ID 24342772
[TLR9]
|
MORPHINE MODULATION OF TOLL LIKE RECEPTORS IN MICROGLIAL CELLS POTENTIATES NEUROPATHOGENESIS IN A HIV -1 MODEL OF CO-INFECTION WITH PNEUMOCOCCAL PNEUMONIAE
,null,
The Journal of neuroscience : the official journal of the Society for Neuroscience
,PubMed ID 22815507
[TLR9]
|
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